Simon Baker

as Roderick Blank

Winona Ryder

as Death Nell / Gillian De Raisx (#101)

Leslie Bibb

as Dr. Miranda Storm

Mindy Cohn

as Trixie

Julie Bowen

as Fiona Wormwood (#29)

Dash Mihok

as Lester

Neil Flynn

as Zack

Patton Oswalt

as Fred

Frances Fisher

as Hope Hartlight (#80)

Daniel Waters

Director