Nicolas Cage

as Edward Malus

Ellen Burstyn

as Sister Summersisle

Kate Beahan

as Sister Willow

Frances Conroy

as Dr. Moss

Molly Parker

as Sister Rose / Sister Thorn

Leelee Sobieski

as Sister Honey

Diane Delano

as Sister Beech

Michael Wiseman

as Officer Pete

Erika-Shaye Gair

as Rowan Woodward

Neil LaBute

Director